Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50551271'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Southwest Jiaotong University
Curated by ChEMBL
Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric scinti...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Southwest Jiaotong University
Curated by ChEMBL
Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Southwest Jiaotong University
Curated by ChEMBL
Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric assayMore data for this Ligand-Target Pair