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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50551271'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551271(CHEMBL4747491)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551271(CHEMBL4747491)
Affinity DataIC50:  22nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551271(CHEMBL4747491)
Affinity DataIC50:  109nMAssay Description:Inhibition of full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed