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Found 1 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM622569'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM622569((7S)-4,7,8-trimethyl-2-((trans-3-((2-(trifluoromet...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent