Found 23 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50364776' TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of PIM1 (unknown origin) up to 120 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of PIM1 kinase (unknown origin) using Biotin-AGAGRSRHSSYPAGT-OH as substrate after 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PIM1 expressed in Escherichia coli using KKRNRTLTV as substrate incubated for 40 mi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length Pim-1 using KKRNRTLTV as substrate after 40 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PIM1 using KKRNRTLTV as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PIM1 expressed in Escherichia coli using LKKRNRTLTV as substrate measured after 40 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Pim1 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of His tagged human recombinant PIM1 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of PIM1 (unknown origin) by coupled kinetic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Inhibition of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue incubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Inhibition of human PIM1 expressed in H1299 cells assessed as inhibition of BAD phosphorylation at S112 in absense of serumMore data for this Ligand-Target Pair
