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Found 2 Enz. Inhib. hit(s) with Target = 'Serine hydroxymethyltransferase, cytosolic' and Ligand = 'BDBM285687'
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University

US Patent
LigandPNGBDBM285687(US10077273, Compound HK-X1 | US10934305, Compound ...)
Affinity DataIC50:  13nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University

US Patent
LigandPNGBDBM285687(US10077273, Compound HK-X1 | US10934305, Compound ...)
Affinity DataIC50:  66nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent