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Found 2 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50337207'
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50337207(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-carbamoy...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50337207(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-carbamoy...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed