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Found 4 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50530453'
TargetSmoothened homolog(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530453(CHEMBL4586057)
Affinity DataKi:  33nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530453(CHEMBL4586057)
Affinity DataKi:  33nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530453(CHEMBL4586057)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530453(CHEMBL4586057)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed