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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/bile acid cotransporter' and Ligand = 'BDBM50576165'
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576165(CHEMBL4875540)
Affinity DataIC50:  14nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells after 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576165(CHEMBL4875540)
Affinity DataIC50:  58nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576165(CHEMBL4875540)
Affinity DataIC50:  8.35E+3nMAssay Description:Inhibition of human NTCP residues (157 to 165) replaced with monkey NTCP -mediated [3H]-TCA uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed