Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/bile acid cotransporter' and Ligand = 'BDBM50576165'
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells after 2 hrsMore data for this Ligand-Target Pair
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of human NTCP residues (157 to 165) replaced with monkey NTCP -mediated [3H]-TCA uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair