Found 7 Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50386885'
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair