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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2' and Ligand = 'BDBM258146'
TargetSodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse Nav1.1/beta1/beta2 expressed in HEK293A cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed