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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 7 subunit alpha' and Ligand = 'BDBM70943'
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM70943(US9546164, 104 | US9694002, 104)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM70943(US9546164, 104 | US9694002, 104)
Affinity DataIC50:  42nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 1 hr in presence of veratridine by sodium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed