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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 8 subunit alpha' and Ligand = 'BDBM630925'
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM630925((S)—N—((R)-(3-chlorophenyl)(4-(trifluoro...)
Affinity DataIC50:  2nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for NaV1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM630925((S)—N—((R)-(3-chlorophenyl)(4-(trifluoro...)
Affinity DataIC50:  2nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for NaV1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent