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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM371523'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371523((R)-N-(6-Fluoropyridin-2-yl)-4-(2-(1-methyl-1H-pyr...)
Affinity DataIC50:  0.300nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371523((R)-N-(6-Fluoropyridin-2-yl)-4-(2-(1-methyl-1H-pyr...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed