Found 22 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 1' and Ligand = 'BDBM50020883' TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.56E+3nMAssay Description:H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.56E+3nMAssay Description:H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.78E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 2.86E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 5.96E+3nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University Of Technology And Economics
Curated by ChEMBL
Budapest University Of Technology And Economics
Curated by ChEMBL
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of mouse GAT1 assessed as reduction in GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 8.15E+4nMAssay Description:Inhibition of GAT1 transport activityMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 4.56E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in D8 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 4.07E+7nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Zhengzhou University
Curated by ChEMBL
Zhengzhou University
Curated by ChEMBL
Affinity DataIC50: 4.07E+7nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
