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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50457691'
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457691(CHEMBL4209849)
Affinity DataIC50:  9nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50457691(CHEMBL4209849)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human GlyT1c expressed in HEK293 cells assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed