Found 8 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50028094'
Affinity DataKi: 0.850nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of [3H]5-HT reuptake into rat frontal cortex synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin re-uptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataKd: 0.290nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERTMore data for this Ligand-Target Pair