Found 3 Enz. Inhib. hit(s) with Target = 'Son of sevenless homolog 1' and Ligand = 'BDBM50459420' 
Affinity DataEC50: 2.10E+4nMAssay Description:Activation of SOS1 in human HeLa cells expressing wild type KRAS assessed as induction of ERK1/2 T202/Y204 phosphorylation incubated for 30 mins by I...More data for this Ligand-Target Pair
Affinity DataEC50: 5.14E+4nMAssay Description:Activation of SOS1 in human NCI-H727 cells expressing KRAS G12V mutant assessed as induction of ERK1/2 T202/Y204 phosphorylation incubated for 30 min...More data for this Ligand-Target Pair
Affinity DataEC50: 5.40E+3nMAssay Description:Activation of human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS comple...More data for this Ligand-Target Pair
