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Found 4 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 2' and Ligand = 'BDBM50576234'
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50576234(CHEMBL4852127)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at recombinant human S1P2 receptor expressed in human CHO cells assessed as EC80 S1P-induced activation incubated for 4 hrs in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50576234(CHEMBL4852127)
Affinity DataIC50:  190nMAssay Description:Displacement of radio labeled-SIP from human recombinant S1P2 receptor expressed in CHO cell membranes measured after 15 mins by radioligand based co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50576234(CHEMBL4852127)
Affinity DataIC50: >1.40E+3nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as EC80 S1P-induced calcium flux measured for 3 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50576234(CHEMBL4852127)
Affinity DataIC50: >2.30E+4nMAssay Description:Agonist activity at human S1P2 receptor expressed in CHO cells assessed as calcium flux measured for 3 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed