Found 7 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 4' and Ligand = 'BDBM23165' 
Affinity DataKi: 23nM ΔG°: -40.5kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Agonist activity at human S1P4 expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22.2nMAssay Description:Agonist activity at human S1P4 receptor assessed as effect on calcium mobilization by Gq dependent whole cell assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at recombinant human S1P4 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human S1P4 expressed in CHO-K1 aequorin cells assessed as calcium accumulation of by luminescence assay in presence of cofactor c...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human recombinant S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMpH: 7.4Assay Description:Agonism of human S1P-4 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
