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Found 2 Enz. Inhib. hit(s) with Target = 'Squalene synthase' and Ligand = 'BDBM50276763'
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50276763(CHEMBL158116)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of SQS in rat liver microsomes assessed as reduction in [3H]FPP conversion to squalene preincubated for 10 mins followed by [3H]FPP additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50276763(CHEMBL158116)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of SQS in rat microsomes using [3H]-FPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed