Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Steroid hormone receptor ERR1' and Ligand = 'BDBM17292'
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  5.90nMAssay Description:Agonist activity at 6his-tagged ERRalpha LBD assessed as recruitment of GST-labeled coactivator Scr2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed