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Found 6 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein' and Ligand = 'BDBM50584879'
TargetStimulator of interferon genes protein(Mus musculus)
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50584879(CHEMBL5092039)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50584879(CHEMBL5092039)
Affinity DataIC50:  3.40E+4nMAssay Description:Displacement of fluorescein-labelled probe from human cytoplasmic domain of STING G230A/R293Q double mutant (155 to 341 residues) by time-resolved FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50584879(CHEMBL5092039)
Affinity DataIC50:  7.80E+4nMAssay Description:Displacement of fluorescein-labelled probe from wild type human His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Mus musculus)
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50584879(CHEMBL5092039)
Affinity DataEC50:  5.20E+4nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50584879(CHEMBL5092039)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to wild type human His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50584879(CHEMBL5092039)
Affinity DataEC50:  6.40E+4nMAssay Description:Binding affinity to human STING G230A/R293Q double mutant cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed