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Found 3 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein' and Ligand = 'BDBM573971'
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataIC50:  1.10nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataKd:  0.0200nMAssay Description:Binding affinity to wild type mouse STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataKd:  3nMAssay Description:Binding affinity to wild type human STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed