Found 8 Enz. Inhib. hit(s) with Target = 'Synaptic vesicular amine transporter' and Ligand = 'BDBM50017712' 
Affinity DataKi: 1nMAssay Description:Inhibition of dopamine uptake at VMAT in bovine chromaffin granule ghostsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]reserpine from human VMAT2 expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Displacement of [3H](+)-syn-Ethyl 1-(2-(2,4-Dioxo-1,2-dihydroquinazolin-3(4H)-yl)ethyl)-4-(4-fluorophenyl)piperidine-3-carboxylate from human VMAT2 e...More data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Displacement of [3H]DHTB from human VMAT2 expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMpH: 8.5Assay Description:The uptake assay was performed in reaction buffer containing 140 mM K2-tartrate, 10 mM Tricine, 10 mM Tris, and 5 mM MgCl2, pH 8.5. Liposomes (1 _...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to human VMAT2 expressed in HEK293 cell membranes by scintillation counting method based saturation binding assayMore data for this Ligand-Target Pair
