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Found 2 Enz. Inhib. hit(s) with Target = 'Synaptic vesicular amine transporter' and Ligand = 'BDBM516376'
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
Neurocrine Biosciences

US Patent
LigandPNGBDBM516376(US11053242, Compound 1-1)
Affinity DataKi:  2.60nMAssay Description:Examples of techniques for determining the capability of a compound to inhibit VMAT2 are provided below. The procedure is adapted from that described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Neurocrine Biosciences

US Patent
LigandPNGBDBM516376(US11053242, Compound 1-1)
Affinity DataKi:  5.20nMAssay Description:Examples of techniques for determining the capability of a compound to inhibit VMAT2 are provided below. The procedure is adapted from that described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent