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Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50365531'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50365531(CHEMBL1957650)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant GST-fused ALK5 using TMB substrate after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50365531(CHEMBL1957650)
Affinity DataIC50:  760nMAssay Description:Inhibition of human recombinant ALK5 activity in human A549 cells assessed as TGFbeta-induced smad2/3 phosphorylation after 2 hrs by fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed