Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50402163' 
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of ALK5-mediated TNFalpha-induced Smad2/3 phosphorylation in human A549 cells preincubated for 2 hrs before addition of TNFalpha after 1 h...More data for this Ligand-Target Pair
