Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor alpha' and Ligand = 'BDBM36487'
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  34nMAssay Description:TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  11nMAssay Description:Effect on human TRalpha transactivation activity in HeLa cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  34nMAssay Description:Effect on human TRalpha transactivation activity in U2OS cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  11nMAssay Description:TRE-driven dual-luciferase reporter assay in human uterine cervical cancer (Hela) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed