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Found 4 Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor beta' and Ligand = 'BDBM50178975'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataIC50:  0.0603nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataEC50:  4.70nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed