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Found 2 Enz. Inhib. hit(s) with Target = 'Thyrotropin receptor' and Ligand = 'BDBM50614125'
TargetThyrotropin receptor(Rattus norvegicus)TBA
LigandPNGBDBM50614125(CHEMBL5270771)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetThyrotropin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50614125(CHEMBL5270771)
Affinity DataIC50:  56nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed