Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 2' and Ligand = 'BDBM50242184' TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Queen'S Center For Biomedical Research
Curated by ChEMBL
Queen'S Center For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human FLAG-tagged TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced intracellular calcium flux after 30 to 60 mins ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Queen'S Center For Biomedical Research
Curated by ChEMBL
Queen'S Center For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 2(Rattus norvegicus)
Queen'S Center For Biomedical Research
Curated by ChEMBL
Queen'S Center For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of TRPM2 in rat INS-1 cells assessed as reduction in ADPR-induced intracellular calcium flux measured after 60 mins by whole cell patch cl...More data for this Ligand-Target Pair
