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Found 2 Enz. Inhib. hit(s) with Target = 'Transitional endoplasmic reticulum ATPase' and Ligand = 'BDBM163144'
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences

Curated by ChEMBL
LigandPNGBDBM163144(US9062026, Table III, Compound 72)
Affinity DataIC50:  68nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences

Curated by ChEMBL
LigandPNGBDBM163144(US9062026, Table III, Compound 72)
Affinity DataIC50: <2.00E+3nMpH: 7.5 T: 2°CAssay Description:The ATPase assay is performed according the following protocol: Purified enzyme (20 nM p97), substrate (20 uM ATP) and a dose titration of compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent