Found 2 Enz. Inhib. hit(s) with Target = 'Transitional endoplasmic reticulum ATPase' and Ligand = 'BDBM50468123' TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Pittsburgh Chemical Diversity Center
Curated by ChEMBL
University Of Pittsburgh Chemical Diversity Center
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Pittsburgh Chemical Diversity Center
Curated by ChEMBL
University Of Pittsburgh Chemical Diversity Center
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:To optimize p97 inhibitors, the C-5 trifluoromethylated trifluoromethylated indole 12 was generated as a promising lead structure. In the ADP-Glo ass...More data for this Ligand-Target Pair
