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Found 2 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM317222'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317222(US9617272, Compound 68 | US9981973, Compound 68)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317222(US9617272, Compound 68 | US9981973, Compound 68)
Affinity DataIC50:  1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent