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Found
1
Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM480499'
Target
Tryptophan 2,3-dioxygenase
(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Ligand
BDBM480499
((2S)-3-(4-(4-(4-(6-fluoro-5H-imidazo[5,1-a]isoindo...)
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Affinity Data
IC50: 220nM
Assay Description:
TDO: For testing, 24 μL of enzyme (TDO) was diluted 100 times with 50 mM KPB to 2400 μL. The concentration of the enzyme solution was 2.6 n...
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Target Info
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Ligand Info
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US Patent
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