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Found 2 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM50289142'
TargetTryptophan 2,3-dioxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289142(3-((E)-2-Pyridin-4-yl-vinyl)-1H-indole | CHEMBL166...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTryptophan 2,3-dioxygenase(Mus musculus)
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50289142(3-((E)-2-Pyridin-4-yl-vinyl)-1H-indole | CHEMBL166...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed