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Found 3 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM50606592'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataKi:  280nMAssay Description:Binding affinity to human TDO assessed as inhibition constant by Cornhish-Bowden methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human TDO by Cornhish-Bowden methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50606592(CHEMBL5219838)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human TDO (19 to 388 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed