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Found 2 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM541886'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541886(US11267824, Example 96 | US11267824, Example 96a)
Affinity DataIC50:  20nMAssay Description:TDO2: Recombinant human TDO comprising amino acids 19-407 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is inc...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541886(US11267824, Example 96 | US11267824, Example 96a)
Affinity DataIC50:  39.9nMAssay Description:TDO2: Recombinant human TDO comprising amino acids 19-407 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is inc...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent