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Found 8 Enz. Inhib. hit(s) with Target = 'Tyrosinase' and Ligand = 'BDBM50205807'
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataKi:  350nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataKi:  350nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataKi:  350nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataIC50:  8.53E+4nMAssay Description:Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed