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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM50490888'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)TBA
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50:  46nMAssay Description:Inhibition of wild type Abl in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)TBA
LigandPNGBDBM50490888(CHEMBL2347725)
Affinity DataIC50:  78nMAssay Description:Inhibition of Abl T315I mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed