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Found 6 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM50530312'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50530312(CHEMBL4436403)
Affinity DataIC50:  251nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50530312(CHEMBL4436403)
Affinity DataIC50:  251nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50530312(CHEMBL4436403)
Affinity DataIC50:  316nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50530312(CHEMBL4436403)
Affinity DataIC50:  316nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50530312(CHEMBL4436403)
Affinity DataEC50:  794nMAssay Description:Induction of human c-ABL phosphorylation at Y245/Y412 residues in bacmam-induced HEK-MSR2 cell lysates by in-cell Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50530312(CHEMBL4436403)
Affinity DataEC50:  794nMAssay Description:Induction of human c-ABL phosphorylation at Y245/Y412 residues in bacmam-induced HEK-MSR2 cell lysates by in-cell Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed