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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1 [T315I]' and Ligand = 'BDBM13216'
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  700nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild-type Abl and Abl T315I kinase activity was measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  590nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair