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Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM102620'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataKi:  3.20nMAssay Description:Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of full-length recombinant human His-tagged BTK expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of BTK autophosphorylation at Y223 in anti-IgM stimulated human Pfeiffer cells after 4 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  10.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  49nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails US Patent