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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM352179'
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM352179
(US9802920, Compound I-3 | {5-Amino-1-[4-(pyridin-2...)
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Affinity Data
IC50: 502nM
Assay Description:
The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...
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Ligand Info
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