Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM400813' TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as subst...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as subst...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of FLAG-tagged BTK (unknown origin) transfected into HEK293T cells incubated for 30 mins followed by ATP addition measured after 20 mins b...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of BTK (unknown origin) transfected in HEK293T cells assessed as reduction in BTK phosphorylation preincubated for 30 mins followed by ATP...More data for this Ligand-Target Pair
