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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK [386-659]' and Ligand = 'BDBM467711'
TargetTyrosine-protein kinase BTK [386-659](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM467711((R)-5-(2-Methyl-4-phenoxyphenyl)-4-oxo-N-(1- (viny...)
Affinity DataIC50:  10nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [386-659](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM467711((R)-5-(2-Methyl-4-phenoxyphenyl)-4-oxo-N-(1- (viny...)
Affinity DataIC50:  15.8nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent