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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1/JAK2' and Ligand = 'BDBM50355501'
TargetTyrosine-protein kinase JAK1/JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataIC50:  31nMAssay Description:Inhibition of JAK2/1 in human T cells expressing CD3 assessed as inhibition of IFNgamma-stimulated STAT1 phosphorylationMore data for this Ligand-Target Pair