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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM127767'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127767(US10251889, Example 140 | US10758542, Example 140 ...)
Affinity DataIC50:  546nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127767(US10251889, Example 140 | US10758542, Example 140 ...)
Affinity DataIC50:  546nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127767(US10251889, Example 140 | US10758542, Example 140 ...)
Affinity DataIC50:  546nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent