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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM391050'
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM391050
(2-(1-(3-((2-(tert-butyl)- 1,1-dioxido-2,3- dihydro...)
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Affinity Data
IC50: 0.0400nM
Assay Description:
The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
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Target Info
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Ligand Info
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US Patent
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