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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM391348'
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM391348
((2S,5S)-isopropyl 5-(3-((2- (tert-butyl)-1,1-dioxi...)
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Affinity Data
IC50: 0.0600nM
Assay Description:
The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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Ligand Info
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Details
US Patent
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