Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50122318' 
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 65nMAssay Description:Inhibition of JAK2 in mouse BAF3 cells assessed as reduction in STAT5 phosphorylation incubated for 2 hrs by Western blot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as reduction in STAT5 phosphorylation incubated for 2 hrs by Western blot methodMore data for this Ligand-Target Pair
Affinity DataKd: 0.480nMAssay Description:Binding affinity to JAK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
